DNA Repair and Mutagenesis Seminars

Environmental agents that can induce DNA damage and mutations are the focus of research in multiple labs within the Center for Environmental Health Sciences, and fostering conversations among experts in this area is part of the Center's mission.  For many years, the DNA Repair And Mutagenesis (DRAM) seminars have brought together scientists from institutions throughout New England who share an interest in the mechanisms of genome maintenance, and the consequences of mutations in humans and model organisms.  The DRAM seminars are held monthly during the academic fall and spring terms and comprise of two talks, for 20 minutes each, by either graduate students, post docs, or principal investigators.  Ample time is reserved for questions both during and after the seminars to promote friendly and engaging discussions.  We hope you will join us for this unique opportunity to meet and network with other scientists.  Refreshments are available before the talks.

Contact 
Nimrat Chatterjee (nimrat@mit.edu), Walker Lab, MIT
Charley Gruber (cgruber@mit.edu), Walker Lab, MIT

Location

MIT Building 56 Room 614

  • Refreshments - 6:45pm
  • Talks - 7:00pm - 8:00pm
  • Networking - 8:00pm - 9:00pm

Dram Seminar Events

October 25, 2018 | 6:45-9:00p | 56-614

DRAM Seminar 10/25/2018

Jacob V. Layer; Weinstock lab, Harvard Medical School. The Role of POLD2 in Genome Stability

Yizhou Joseph He; Chowdhury lab, Harvard Medical School. DYNLL1 inhibits DNA end resection in BRCA1-deficient cells and regulates PARP inhibitor sensitivity

November 15, 2018 | 6:45-9:00p | 56-614

DRAM Seminar 11/15/2018

Seungwoo Chang; Loparo lab, Harvard Medical School. Conformational basis in pathway choice of lesion-stalled replisomes

Xiao-Feng Zheng; Chowdhury lab, Harvard Medical School. A novel CDK5-PP4 signaling cascade drives 53BP1 to sites of DNA damage

December 6, 2018 | 6:45-9:00p | 56-614

DRAM Seminar 12/6/2018

Bill Thilly; Thilly lab, MIT. An unsupported and costly assumption: human organogenic and pathogenic stem cells are eukaryotic

Norah Owiti; Engelward lab, MIT. Incorporation and Repair of Uracil at Highly Transcribed Genes in S. cerevisiae

January 17, 2019 | 6:45-9:00p | 56-614

DRAM Seminar 1/17/2019

Chuxuan Li; Delaney lab, Brown University. Histone H2A Variants Enhance Global Uracil Excision in Nucleosomes

Deyu Li; Li lab, Univeristy of Rhode Island. Chemical Biology of DNA Damage and Repair

February 14, 2019 | 6:45-9:00p | 56-614

DRAM Seminar 2/14/2019

Christiane Brugger; Deaconescu lab, Brown University. Structural Basis for RpoS Regulation

Sumeet Nayak; Cantor lab, U. Mass Medical. TLS counteracts the replication stress response

March 7, 2019 | 6:45-9:00p | 56-614

DRAM Seminar 3/7/2019

Judit Jimenez Sainz; Jensen lab, Yale University. Illuminating Pathogenicity of BRCA2 Variants of Uncertain Significance

Rajula Elango; Scully lab, Harvard Medical School. Coordination of stalled fork repair by the Fanconi Anemia gene product SLX4

April 11, 2019 | 6:45-9:00p | 56-614

DRAM Seminar 4/11/2019

Lexi Gehring; Gardner lab, New England Biolabs. Building a comprehensive understanding of 8-oxo-guanine repair in Archaea

Arvind Panday; Scully lab, Harvard Medical School. Genetic interaction between BRCA1 and FANCM in stalled fork repair

May 9, 2019 | 6:45-9:00p | 56-614

DRAM Seminar 5/9/2019

Connor Clairmont; D’Andrea lab, Harvard Medical School. Regulation of DNA double strand break repair in homologous recombination deficient cancers

Nimrat Chaterjee; Walker lab, MIT. Small molecule adjuvant enhances tumor cell response to chemotherapy by disrupting REV1/REV7-mediated mutagenic translesion synthesis