Facilities Cores


Page Sections:

Animal Models and Pathology Facilities Core

Bioanalytical Facilities Core

Genomics and Bioinformatics Facilities Core

Facilities Cores

The three state-of-the-art Facilities Cores provide Center members with the technologies, expertise and services that are not available from other sources at MIT. The following Facilities Cores reflect the new research directions of the Center:

Animal Models and Pathology
Facilities Core
Director: Prof. James Fox


The Animal Models and Pathology Facilities Core

A substantial fraction of the research carried out in the CEHS involves the use of animal models of human disease. To meet this need, the Animal Models and Pathology Facilities Core, directed by Prof. James Fox, provides numerous services to Center members, including overseeing husbandry for all the animals used by CEHS members (rats and mice), development of transgenic knock-out and knock-down animal models, histopathology, advanced tissue imaging, DNA sequencing, real-time PCR and other technologies related to cell and molecular biology, as well as the services of board certified pathologists. The Core is comprised of the facilities, services and expertise of the Division of Comparative Medicine at MIT, directed by James Fox.

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Bioanalytical Facilities Core
Co-Directors: Drs. John Wishnok
and Koli Taghidazeh


The Bioanalytical Facilities Core

This Facilities Core is co-directed by Drs. John Wishnok and Koli Taghizadeh.  The Bioanalytical Facilities Core is a central resource in analytical chemistry, separation science and proteomics for CEHS members and provides research participants with analytical expertise, training, and access to state-of-the-art instrumentation. This Core is home to a world-class chromatography and mass spectrometry facility, including an accelerator mass spectrometer, that provides CEHS members with state-of-the-art chemical molecular separation, identification and quantification capabilities. The Bioanalytical Facilities Core is comprised of the Bioanalytical Laboratory in Building NE47 (room 281) and the Biological Engineering Mass Spectrometry Facility in Building 56 (room 747). Training and assistance is provided by the Directors.

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The Genomics and Bioinformatics
Facilities Core
Director: Dr. Rebecca Fry


The Genomics and Bioinformatics Facilities Core

The goal of this Core, led by Dr. Rebecca Fry, is to provide state-of-the-art tools, services and expertise in the areas of genomics and bioinformatics to Center members. This Core provides access to a variety of different genomics platforms (i.e., Affymetrix GeneChips, Agilent arrays, oligonucleotide and cDNA arrays, and antibody arrays) and to the Bioinformatic tools and expertise required to analyze genomic scale data. This Core provides training and expertise to the members of all CEHS labs using this experimental approach. 

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