2018-2019 PILOT PROJECT RECIPIENTS

The MIT Center for Environmental Health Sciences, through support from the NIH-NIEHS Center Grant P30-ES002109, has awarded two basic science and one translational pilot projects with a start date of June 1, 2018 from the April 2018 pilot project call released this year.

BASIC SCIENCE APPLICATIONS

Sequestration of Toxic Organics from UV-treated Drinking Water

This project proposes to exploit biologically derived strategies for water cleanup, also known as bioremediation, to address the limitations of physicochemical methods.

  • Angela Belcher
  • Professor, Biological Engineering and Materials Science and Engineering

Examining Pore-Scale Biogeochemical Controls on Arsenic Speciation and Mobilization within Oxidizing, Reduced, and Sulfidic Soils and Sediments

Coupled biogeochemical-physical processes control the cycling for a myriad of soil constituents. In this pilot project, the researchers will move forward in two general research areas: 1) further development of micromodel/microfluidic devices that mimic soil conditions and facilitate in-situ measurements, and 2) use these devices to conduct basic scientific research.

  • Benjamin Kocar
  • Assistant Professor, Civil and Environmental Engineering

Formation of Gas-phase Toxics from the Atmospheric Oxidation of Particulate Organics

We propose exploratory laboratory studies that seek to identify and quantify the gas-phase products that evolve from organic particulate matter upon atmospheric oxidation, with a particular focus on the formation of known gas-phase air toxics.

  • Jesse Kroll
  • Associate Professor, Civil and Environmental Engineering and Chemical Engineering

Lead-chelating Molecular Nanoribbons

We propose an alternative to adsorption-based filtration materials for water remediation in which we exploit chelation from the surface of supramolecular nanoribbons as a proof-of-principle technology.

  • Julia Ortony
  • Assistant Professor, Materials Science and Engineering

TRANSLATIONAL APPLICATIONS

Investigating how Exposure to Oxidative Stress Impacts Cardiac Physiology

In this pilot study, we will employ a human induced pluripotent stem cell (hiPSC) model of cardiac development to mechanistically dissect the impact of POS on DNA repair and differentiation during cardiac lineage commitment.

  • Laurie Boyer
  • Associate Professor, Biology and Biological Engineering

THERON RANDOLPH APPLICATIONS

Properties of Saliva Associated with Contaminant Exposure

With this pilot project, we aim to generate a system-based understanding of how saliva properties and functions correlate with contaminant exposure.

  • Katharina Ribbeck
  • Associate Professor, Biological Engineering