The MIT Center for Environmental Health Sciences, through support from the NIH-NIEHS Center Grant P30-ES002109, has awarded four basic science and one translational pilot projects with a start date of July 1, 2019 from the April 2019 pilot project call released this year.
The one funded basic science application is:
Elizabeth NolanProfessor, Chemistry
“How Microcins Kill Zoonotic Bacteria;
The goal of this pilot study is to understand the modes of action of two peptidic natural products that have been implicated in mediating bacterial competition involving zoonotic bacteria and the microbiome.
The two funded translational applications are:
John M. Essigmann and Robert CroyProfessor and Research Scientist, Biological Engineering and Center for Environmental Health Sciences
“Identification of Mutational Spectra in Cell-free DNA after Exposure of Rats to Aflatoxin B1;
In this pilot study, we will determine the mutational fingerprint of AFB1 in the gDNA of the liver and cfDNA from blood in the Fischer 344 rat.
Desiree PlataAssistant Professor, Civil and Environmental Engineering
“Electrochemically-active Filters for the Destruction of N-nitrosodimethylamine;
This pilot project seeks to develop a single-film electroactive membrane composed of carbon nanotubes (CNTs) that can be readily incorporated into existing filtration devices at scales from cm2 to m2.