BASIC SCIENCE APPLICATIONS
Investigating Uncertainties in Satellite – Derived Estimates of Premature Mortality Associated with Particulate Matter
The goal of this project is to investigate the uncertainties in satellite-derived-PM2.5 and the implications for estimated health risks world-wide.
- Colette Heald
Associate Professor, Civil and Environmental Engineering
Understanding and Ameliorating Arsenic – Induced Protein Misfolding
The objective of this project is to test the hypothesis that pre-conditioning cells by activating protein misfolding stress responses with small molecules prior to exposure to arsenic will reduce arsenic’s cytotoxicity.
- Matthew Shoulders
Assistant Professor, Chemistry
TRANSLATIONAL APPLICATIONS
Sulfur DNA modifications in gut microbes confer resistance to oxidative stress
The goals of these studies are to characterize gut microbes that possess phosphorothioate (PT) modifications of their genomes and to assess the impact of PT modifications and the compositions of the gut microbiome during inflammation.
- Peter Dedon
Professor, Biological Engineering - James Fox
Professor and Director, Biological Engineering and Division of Comparative Medicine - Eric Alm
Associate Professor, Biological Engineering
The role of arsenic in adult brain pathology. Translational studies in the mouse.
The purpose of this project is to develop preliminary information on the potential of certain compounds in the environment to cause neuropathological changes in the brain.
- Steve Tannenbaum
Professor, Biological Engineering, Chemistry, and Toxicology
Can microbiome therapy cure IBD in sick dogs?
The primary goal of this project is to test whether Fecal Microbiota Transplant can cure Inflammatory Bowel Disease in canine patients. The secondary goal of this project is to generate preliminary data for an Investigational New Drug application for human trials.
- Eric Alm
Associate Professor, Biological Engineering - Susan Erdman
Principal Research Scientist, Division of Comparative Medicine
Measuring Chemical Fluxes from Contaminated Sediments using Eddy Correlation, Fiber-optic-based Optical Chemical Sensing, and the SWIFT flux tracer concept
The broad projective of the project is to develop a new technology, based on eddy correlation, to rapidly measure benthic releases of chemicals from a large range of contaminated sediments.
- Harold Hemond
Professor, Civil and Environmental Engineering