2016-2017 PILOT PROJECT RECIPIENTS

The MIT Center for Environmental Health Sciences, through support from the NIH-NIEHS Center Grant P30-ES002109, has awarded one basic science and one translational pilot projects with a start date of September 1, 2016 from the May pilot project call released this year.

BASIC SCIENCE APPLICATIONS

From Understanding of Interrupting Bacterial Pathogenesis

These pilot studies are expected to demonstrate that chemotactic sensing occurs via a specific molecular motion.

  • Gabriela Schlau-Cohen
  • Assistant Professor, Chemistry

TRANSLATIONAL APPLICATIONS

Lineage Sequencing’ for Deeper Insights into Exposure-induced Somatic Mutations

We wish to measure mutation accumulation process within cells with and without mismatch repair deficiency.

  • Paul Blainey
  • Assistant Professor, Biological Engineering

Connecting Mercury Sources to Community Exposure through Modeling

This proposal connects community-driven concerns to translational application with a focus of preventative action, linking to regulation and policy. It thus informs both upstream (global and national policy and regulation) and point-of-exposure efforts to improve human health.

  • Noelle Selin
  • Associate Professor, Institute for Data Systems and Society, Department of Earth, Atmospheric and Planetary Sciences

THERON RANDOLPH APPLICATIONS

Nickel Allergy and Proinflammatory Proteins

The goal of this pilot research initiative is to evaluate a putative role for the proinflammatory proteins calprotectin (CP, S100A8/S100A9) and psoriasin (S100A7) in contact hypersensitivity to nickel, a metal ion that is a component of many consumer products and causes skin allergy in humans.

  • Elizabeth Nolan
  • Associate Professor, Chemistry