Contact: Core Managers: Dr. Bogdan Fedeles and Dr. Michael DeMott
The Bioimaging and Chemical Analysis Facilities Core provides Center members with state-of-the-art tools and techniques for the characterization and quantification of chemical substances and modifications of cellular compounds ranging from small molecules, e.g., single metal ions, metabolites and reaction products, to nucleic acid oligomers and intact proteins. The Core resources also include a suite of data-handling software for qualitative and quantitative analyses. As a resource for CEHS members, the Core allows researchers to use the facilities at two levels: fully trained users, and supervised analyses.
- Tandem Triple Quadrupole Mass Spectrometer (Quantatitation, structure elucidation)
- Quadrupole Time-of-Flight Mass Spectrometer (Exact masses, Metabolomics)
- Thermo Fisher Orbitrap Q Exactive (Exact masses, Metabolomics)
- Inductively Coupled Plasma Mass Spectrometer (Elemental determination)
- Bioinformatics (Database searching, pathway analysis)
- Quantitation (Spectral counting, iTRAQ, multiple reaction monitoring)
- Custom software (Deconvolution, unique protein/peptide modifications)
- Statistics (Regression analysis, principal component analysis, clustering)
- Flow Cytometry (Accuri C6)
- Biomolecular Imager (Typhoon 7000 FLA)
- Flow Cytometry (CytoFLEX)