This course is intended for investigators at all levels who are interested in next-generation sequencing resources and applications available to the Harvard community. It will include an introductory lecture on next-generation sequencing technology and sample preparation, with additional lectures data interpretation and application of this analysis in genomics. Participants will gain a fundamental knowledge of sequencing methodologies and learn how to apply them to studying genetic variation and human diseases. The course is from 1:00PM to 4:15PM at 185 Cambridge Street, Simches Room 3.110.