Dram Seminars - Past
DRAM Seminar 12/9/2021
Rebecca Brown (Freudenreich Lab, Tufts University): Components of the THO and TRAMP complexes prevent transcription-replication conflicts and protect against fragility of expanded CAG repeats
Allen Su (Lee Lab, MIT Koch Institute): Cohesin Mitigates Oncogenic Replication Stress
DRAM Seminar 11/18/2021
Anastasia Rastokina (Mirkin Lab, Tufts University): Insight into GAA repeat expansion in mammalian cells
Judit JimenezSainz (Jensen Lab, Yale University): Cancer missense mutations in the BRC repeats of BRCA2 protein disrupt RAD51 binding and activity leading to chemotherapeutic sensitivity
DRAM Seminar 10/14/2021
Vladimir Seplyarskly (Sunyaev Lab, Harvard University): A site-specific mutation rate model uncovers Pol III related hypermutability
Prachi Kharade (Thilly Lab, MIT): Alzheimer's disease as a clonal neoplasia
DRAM Seminar 5/13/2021
Simona Dalin (Beroukhim Lab, DFCI/Broad and Getz Lab, MGH/Broad): Mutations and Structural Variants arising during double-strand Break Repair
DRAM Seminar 4/15/2021
The seminar will start at 5:30PM via zoom at: https://mit.zoom.us/j/95616196931
Ryan McGinty (Sunyaev Lab, Harvard Medical School): Short tandem repeat-induced mutagenesis in the human germline
DRAM Seminar 3/11/2021
Norah Owiti (Engelward Lab, MIT): Effect of N-Nitrosodimethylamine on gene expression in mice with varied DNA repair capacity.
Nilisha Pokhrel (Lohman Lab, New England Biolabs): T4 DNA ligase: the quest for rate-limiting step and beyond
DRAM Seminar 2/11/2021
Daniel Laverty (Nagel Lab, HSPH): Rev7 Dimerization and The Role of Shieldin in Complex Break Repair.
Elena Sapede (Haber Lab, Brandeis): Nonhomologous Tails Impact Mismatch Correction in Divergent Repeats During SSA Repair
DRAM Seminar 1/14/2021
Julia Hisey (Mirkin Lab, Tufts): Replication-independent instability of Friedrich's Ataxia GAA repeats during chronological aging.
Niraj Joshi (D'Andrea Lab, DFCI): FANCG is a Negative Regulator of FANCA-mediated Single-Strand Annealing and DNA End-Resection