DRAM Seminar 12/14/2023
Ryan McGinty (Sunyaev Lab, Harvard Medical School): Modeling replication slippage explains short tandem repeat lengths in the human genome
Aleem Syed (D'Andrea Lab, Dana Farber Cancer Institute): Allosteric inhibitors of DNA polymerase theta ATPase activity
DRAM Seminar 11/9/2023
Daniel Laverty (Nagel Lab, Harvard T.H. Chan School of Public Health): A mismatch repair-independent mechanism resolves insertion-deletion loops in transcribed DNA
Vladimir Seplyarskiy (Sunyaev Lab, Harvard Medical School): Evolution of mutational processes in mammals
DRAM Seminar 10/12/2023
Felix Zhou (Haber Lab, Brandeis University): The role of Arp2/3 and myosins in double-strand break mobility is S. cerevisiae
Sateja Paredkar (Bindra Lab, Yale University): PARG inhibition leads to the formation of cytotoxic PARP1 aggregates
DRAM Seminar 5/11/2023
Nimrat Chatterjee (Chatterjee Lab, University of Vermont): Translesion synthesis, host genome instability and RNA virus pathogenesis
Allen (Xiofeng) Su (Su Lab, Center for Prostate Disease Research (CPDR)/NCI/MIT): RAD21 promotes repair of oncogenic DNA lesions arising from transcription-replication conflicts
DRAM Seminar 4/13/2023
Robert Sobol (Sobol Lab, Brown University): Discussing new areas of intererest for base excision repair - from the aging neuron to replication stress
Stamatis Papathanasiou (Pellman Lab, Dana Farber Cancer Institute): Micronuclei as a source of transgenerational defects in transcription
DRAM Seminar 3/9/2023
Sharon Cantor (Cantor Lab, UMass Chan Medical School): The Gap Model and Predicting Chemotherapy Response
Mia Petljak (Golub Lab, Broad Institute): Mechanisms of APOBEC3 Mutagenesis in Human Cancer Cells
Harris Lecture: Ben Van Houten
“Observing DNA Repair Proteins Protecting our Genomes from Cancer: From Single Molecules to Cells". For more information about Professor Ben Van Houten, please click here.
DRAM Seminar 2/9/2023
Jullien Flynn (Yamashita Lab, Whitehead Institute): Perturbing satellite DNA stability with Bloom mutations and nutritional stressors in Drosophila
Tycho Mevissen (Walter Lab, Harvard Medical School): Transcription-coupled DNA Repair in a Test Tube
DRAM Seminar 1/12/2023
Sarah R. Hengel (Berstein Lab, University of Pennsylvania, prior Tufts University): SWSAP1-SWS1 stimulates RAD51 D-loop formation on RPA-coated ssDNA